Human Papillomavirus: The Equal Opportunity Pathogen

Equal Opportunity.

Human papillomavirus vaccine--opportunity and challenge.

In this issue of the Journal, we publish three Original Articles,1-3 two Perspective articles,4,5 two editorials,6,7 a letter to the editor,8 and an audio interview9 on the subject of human papillomavirus (HPV). We bring together this unique body of information in response to the enormity of the health problems that stem from HPV and the broad interest that has been kindled by the possibility o...

Equal opportunity for all.

By sequencing tens of millions of TCRa transcripts from naive mouse CD8 T cells, Genolet et al (2012) show that the TCRa repertoire is at least as diverse as the TCRb repertoire. This overturns a long held view in the field that recombination of the Tcra locus occurs in a co-ordinate sequential bidirectional manner that relies on proximity of Va and Ja gene segments. The observation that rearra...

Tobacco: an equal-opportunity killer?

In their article, Jamrozik et al (see page 258) have explored the mortality hazard associated with smoking by gender and provide evidence that Australian men and women with similar smoking histories (namely, cigarettes smoked per day and time since quit) experience similar rates of death from smoking. Given the limitations of the data in this study, caution should be used in interpreting these ...

On the Design of Equal-opportunity Policies

We study in this paper mechanisms to construct equal-opportunity policies for resource allocation. In a model where individuals enjoy welfare as a function of the e ort they expend, and the amount of a socially provided resource they consume, the aim is to allocate the social resource so that the inequality of welfare across individuals at the same relative e ort level is minimized. In doing so...